| Journal of Animal Biology & Therapeutics
Received: 10 August 2026; Revised: 13 September 2026; Accepted: 25 September 2026; Published Online: 28 September 2026.
J. Anim. Biol. Ther., 2026, 1(1), 26704 | Volume 1 Issue 1 (September 2026) | DOI: https://doi.org/10.64189/abt.26704
© The Author(s) 2026
This article is licensed under Creative Commons Attribution NonCommercial 4.0 International (CC-BY-NC 4.0)
A Case Report of Babesia sp. in Feline Host: Diagnosis
and Successful Outcome
Farhan Eravaramkunnath,
1*
Fathima Dhina,
2
Arya Ramachandran Nair Sujatha Devi
3
and Bindhu Lakshmanan
4
1
The Cochin Pet Hospital, Ernakulam, Kerala, 682020, India
2
College of Veterinary & Animal Sciences, Mannuthy, Kerala, 680651, India
3
District Veterinary Centre, Palakkad, Kerala, 678001, India
4
Department of Veterinary Parasitology, College of Veterinary & Animal Sciences, Mannuthy, Kerala, 680651, India
*Email: drfarhanhamza@gmail.com (Farhan Eravaramkunnath)
Abstract
Babesiosis is a disease of mammals including cats caused by a hemoparasitic protozoan Babesia sp. affecting
erythrocytes and vascular endothelium. A two-year-old, intact male, Persian cat with an indooroutdoor
lifestyle was presented to the District Veterinary Centre, Palakkad, Kerala, with a history of persistent vomiting,
progressive lethargy, and anorexia. Hematological analysis demonstrated marked anemia, thrombocytopenia,
and leukopenia. Microscopic examination of Giemsa-stained peripheral blood smear prepared from ear tip
revealed the presence of Babesia organisms within erythrocytes. Based on morphological characteristics, a
presumptive diagnosis of feline babesiosis was made; however, definitive species-level identification remained
inconclusive due to the absence of molecular characterization. The cat was treated with a combination therapy
consisting of diminazene aceturate and doxycycline. The animal showed rapid clinical improvement, with
resolution of clinical signs and had an uneventful recovery. This case highlights the importance of hematological
and blood smear evaluation for early detection of feline babesiosis, alongside low-cost molecular methods for
species confirmation and the potential efficacy of combination therapy.
Keywords: Babesia sp.; Cat, Kerala; Diminazene aceturate; Anemia; Palakkad.
1. Introduction
Babesia

BabesiaB. felisB. catiB.
herpailuriB. pantherae


B. canis B. gibsoni 


Babesia felis





Babesia
 







              


             

          


         
         
        
     



             
Babesia















































Babesia

The animal was initially treated with an intramuscular injection of diminazene aceturate (Berenil®, MSD) at a
dose of 3.5 mg/kg. Additionally, doxycycline was administered orally at 10 mg/kg (Doxypet, Savavet) for a
duration of 21 days. Supportive care, including fluid administration, multivitamin injections, and oral
haematinics, was also provided as per the requirement. The animal was handled humanely throughout the
diagnostic and therapeutic procedures. All clinical interventions were performed in accordance with standard
veterinary practices, with appropriate measures taken to minimize pain, stress, and suffering. Care was taken

               
improvement. After 21 days, hematological parameters returned to normal and the cat had an uneventful
recovery.
3. Results and discussion








et al.
et al.



Babesia panickeri   et al.          







et al.et al.


            




           

Mycoplasma haemofelis
Babesia felisBabesia
Babesia






BabesiaB. felis, B. canis B. lengau


        
 Babesia          
 Babesia
   Babesia         

             

Babesia

     
             

 





       
 








            





               







             





References
[1]
V. P. Panicker, A. K. Sreedharan Nair, A. Narayanan, S. George, S. V. Hameed, Molecular Identification
of a Novel Species, Babesia panickeri sp. nov., from a Naturally Infected Domestic Cat of India and Its
Comparison with Canine Babesia Isolates, Acta Parasitologica, 2020, 65, 913-918, doi:
10.2478/s11686-020-00228-9
[2]
Babesia gibsoni Infection
in a Cat with Immune-Mediated Haemolytic Anaemia and Thrombocytopenia, Animals, 2023, 13, 2128,
doi: 10.3390/ani13132128.
[3]
G. Baneth, M. J. Kenny, S. Tasker, Y. Anug, V. Shkap, A. Levy, S. E. Shaw, Infection with a Proposed New
Subspecies of Babesia canis, Babesia canis subsp. presentii, in Domestic Cats, Journal of Clinical
Microbiology, 2004, 42, 99-105, doi: 10.1128/jcm.42.1.99-105.2004.
[4]
S. Remesar, J. L. Arnal, A. Gómez, A. Prieto, D. García-Dios, A. Benito, M. Rodríguez, G. Fernández, R.
Panadero, C. López, P. Díez-Baños, P. Díaz, A Case Report of Fatal Feline Babesiosis Caused by Babesia
canis in North Western Spain, BMC Veterinary Research, 2022, 18, 177, doi: 10.1186/s12917-022-
03287-4.
[5]
P. R. Aziz, K. Jamwal, A. Patial, D. Thakur, A Case Presentation of Babesiosis in A Mongrel Cat, Advances
in Research, 2025, 26, 139-144, doi: 10.9734/air/2025/v26i41393.
[6]
S. V. Mudaliar, G. R. Achary, V. S. Alwar, On a Species of Babesia in an Indian Wild Cat (Felis catus),
Indian Veterinary Journal, 1950, 26, 392-395.
[7]
J. P. Varshney, P. S. Chaudhary, V. V. Deshmukh, Feline Babesiosis: A Case Report, Intas Polivet, 2008,
9, 288-291.
[8]
L. Sabu, R. Sreekrishnan, K. Devada, T. S. Rejitha, B. Lakshmanan, Babesia Species in a CatA Case
Report, Journal of Veterinary Parasitology, 2013, 27, 68-69.
[9]
S. P. Rejimon, V. M. Mathai, S. B. Sarangom, A. Gopinath, C. S. Neethu, S. Sundaran, Piroplasmosis in a
Domestic Cat-A Case Report, The Indian Veterinary Journal, 2022, 99, 66-67.
[10]
P. Vincy, P. V. Tresamol, Prevalence of Gastro-Intestinal and Haemoparasitic Infections among
Domestic Cats of Kerala, Journal of Parasitic Diseases, 2023, 47, 562-565, doi: 10.1007/s12639-023-
01599-2.
[11]
C. Jackson, F. J. Dunning, Biliary Fever (Nuttalliosis) of the Cat: A Case in the Stellenbosch District,
Journal of the South African Veterinary Medical Association, 1937, 8, 83-88.
[12]
J. McNeil, Piroplasmosis of the Domestic Cat, Journal of the South African Veterinary Medical
Association, 1937, 8, 88-90.
[13]
O. M. Radostits, C. C. Gay, K. W. Hinchcliff, P. D. Constable, Veterinary Medicine: A Textbook of the
Diseases of Cattle, Horses, Sheep, Pigs and Goats, 10th ed., Elsevier, 2006.
[14]
P. Abinaya, K. Rajkumar, A. A. Prabavathy, P. Vijayalakshmi, Primaquine Phosphate for Therapeutic
Management of Feline Babesiosis-A Case Report, Intas Polivet, 2020, 21, 257-259.
[15]
A. L. Ayoob, J. Prittie, S. G. Hackner, Feline babesiosis, Journal of Veterinary Emergency and Critical Care,
2010, 20, 90-97, doi: 10.1111/j.1476-4431.2009.00493.x.
[16]
A. M. Bosman, E. H. Venter, B. L. Penzhorn, Occurrence of Babesia felis and Babesia leo in Various Wild
Felid Species and Domestic Cats in Southern Africa, based on Reverse Line Blot Analysis, Veterinary
Parasitology, 2007, 144, 33-38, doi: 10.1016/j.vetpar.2006.09.025.
[17]
A. M. Bosman, M. C. Oosthuizen, E. H. Venter, J. C. Steyl, T. A. Gous, B. L. Penzhorn, Babesia lengau
Associated with Cerebral and Haemolytic Babesiosis in Two Domestic Cats, Parasites & Vectors, 2013,
6, 128, doi: 10.1186/1756-3305-6-128.
Publisher Note: The views, statements, and data in all publications solely belong to the authors and
contributors. GR Scholastic is not responsible for any injury resulting from the ideas, methods, or products
mentioned. GR Scholastic remains neutral regarding jurisdictional claims in published maps and institutional
affiliations.
Open Access
This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which
permits the non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format,
as long as appropriate credit to the original author(s) and the source is given by providing a link to the Creative
Commons License and changes need to be indicated if there are any. The images or other third-party material
in this article are included in the article's Creative Commons License, unless indicated otherwise in a credit line
to the material. If material is not included in the article's Creative Commons License and your intended use is
not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly
from the copyright holder. To view a copy of this License, visit: https://creativecommons.org/licenses/by-
nc/4.0/
© The Author(s) 2026